16th HHT International Scientific Conference

Where Breakthroughs Set Sail

October 12–16, 2026 | Cape Cod, Massachusetts

Conference Agenda

Time (EDT)
Session
4:00 PM – 7:00 PM
Registration

Registration and Check-In

4:00 PM – 7:00 PM (EDT) La Sallette
7:00 PM – 10:00 PM
Reception

Welcome Reception

7:00 PM – 10:00 PM (EDT) Ocean Terrace
7:00 AM – 8:15 AM
Breakfast

General Breakfast

7:00 AM – 8:15 AM (EDT) Bay Pines Pavilion
8:30 AM – 9:00 AM
Opening

Welcome and Patient Story

8:30 AM – 9:00 AM (EDT) Mansion Ballroom
Marianne Clancy
Marianne Clancy, MPA
CEO and Managing Director, Strategic Partnerships
Cure HHT
9:00 AM – 10:00 AM
Keynote

Genetic Determinants of HHT: A Retrospective and Forward-Looking Keynote

9:00 AM – 10:00 AM (EDT) Mansion Ballroom
Doug Marchuk
Doug Marchuk, PhD
James B. Duke Professor
Duke University Medical Center
10:00 AM – 10:30 AM
Featured

Novel Therapeutics in HHT

10:00 AM – 10:30 AM (EDT) Mansion Ballroom
Hanny Al-Samkari
Hanny Al-Samkari, MD
The Peggy S. Blitz Endowed Chair in Hematology/Oncology and Co-Director HHT Center of Excellence
Massachusetts General Hospital; Associate Professor, Harvard Medical School
10:30 AM – 10:50 AM
Break

Break

10:50 AM – 12:35 PM
Session 2

Transforming HHT Research

10:50 AM – 12:35 PM (EDT) Mansion Ballroom
10:50 AM – 11:20 AM
Invited

Spatial Transcriptomics and High-Resolution Tissue Mapping

10:50 AM – 11:20 AM (EDT) Mansion Ballroom
Gaddy Getz
Gaddy Getz, PhD
Director, Cancer Genome Computational Analysis Group; Professor of Pathology
Broad Institute; Harvard Medical School
William Sellers
William Sellers, MD
Core Institute Member
Broad Institute, Dana-Farber Cancer Institute, Harvard Medical School
12:35 PM – 1:45 PM
Lunch

Lunch

12:35 PM – 1:45 PM (EDT) Bay Pines Pavilion
2:00 PM – 3:00 PM
Session 3

Advocacy and Research Infrastructure

2:00 PM – 3:00 PM (EDT) Mansion Ballroom
Mark Vieth
Mark Vieth
Senior Vice President
CRD Associates
Andrei Kindzelski
Andrei Kindzelski, MD, PhD
Program Director
National Heart, Lung, and Blood Institute
3:00 PM – 3:30 PM
Sponsor

Podium Presentation

3:00 PM – 3:30 PM (EDT) Mansion Ballroom
Diagonal Therapeutics
3:30 PM – 3:45 PM
Poster Pitches

Poster Pitches

3:30 PM – 3:45 PM (EDT) Mansion Ballroom
4:00 PM – 6:00 PM
Session 4

Poster Session

4:15–5:00 PM: judging for even-numbered posters
5:00–5:45 PM: judging for odd-numbered posters

4:00 PM – 6:00 PM (EDT) Carriage House
7:00 AM – 8:15 AM
Breakfast

General Breakfast

7:00 AM – 8:15 AM (EDT) Bay Pines Pavilion
8:30 AM – 8:50 AM
Opening

Welcome and Patient Story

8:30 AM – 8:50 AM (EDT) Mansion Ballroom
8:50 AM – 11:40 AM
Session 5

Clinical Trial Plenary

Participating programs: Alnylam, Atavistik, Diagonal, Tectonic, Terremoto, Vaderis, TrUST HHT, Pazopanib

8:50 AM – 11:40 AM (EDT) Mansion Ballroom
10:40 AM – 11:00 AM
Break

Break

11:40 AM – 12:30 PM
Session 6

Complicated Case Presentations and Scientific Conundrums

11:40 AM – 12:30 PM (EDT) Mansion Ballroom
12:45 PM – 1:45 PM
Lunch

Lunch

12:45 PM – 1:45 PM (EDT) Bay Pines Pavilion
2:00 PM – 2:45 PM
Session 7

Regulatory Science and Pathways to Drug Approval: Regulatory Landscape and FDA Pathways for HHT Therapeutics

2:00 PM – 2:45 PM (EDT) Mansion Ballroom
Tanya Wroblewski, MD
Division Director Division of Nonmalignant Hematology Office of Cardiology, Hematology, Endocrinology, and Nephrology Office of New Drugs Center for Drug Evaluation and Research
2:45 PM – 4:30 PM
Session 8

Disease Mechanisms and Vascular Biology

2:45 PM – 4:30 PM (EDT) Mansion Ballroom
2:45 PM – 3:15 PM
Invited

PIEZO Pathways and Mechanotransduction

2:45 PM – 3:15 PM (EDT) Mansion Ballroom
Hyojin Park
Hyojin Park, PhD
Department of Cellular and Molecular Physiology, Yale University School of Medicine
7:00 AM – 8:15 AM
Breakfast

General Breakfast

7:00 AM – 8:15 AM (EDT) Bay Pines Pavilion
8:30 AM – 8:50 AM
Opening

Welcome and Talk

8:30 AM – 8:50 AM (EDT) Mansion Ballroom
Hara Levy, MD
Professor
Department of Pediatrics, School of Medicine and Public Health, University of Wisconsin, Madison, Wisconsin
8:50 AM – 10:40 AM
Session 9

Clinical Manifestations, Bleeding and Anemia in HHT

8:50 AM – 10:40 AM (EDT) Mansion Ballroom
8:50 AM – 9:20 AM
Invited

Maternal–Fetal Iron Biology and Implications for HHT

8:50 AM – 9:20 AM (EDT) Mansion Ballroom
Michael Georgieff
Michael Georgieff, MD
Professor and Vice Chair
Department of Pediatrics, University of Minnesotta
10:40 AM – 11:00 AM
Break

Break

11:00 AM – 12:30 PM
Session 10

Registries, Cohorts, and Population Genetics

11:00 AM – 12:30 PM (EDT) Mansion Ballroom
11:00 AM – 11:30 AM
Invited

BVMC and MARS Updates

11:00 AM – 11:30 AM (EDT) Mansion Ballroom
Helen Kim
Helen Kim, PhD
Department of Anesthesia and Preoperative Care
University of California, San Francisco
12:30 PM – 1:40 PM
Lunch

Lunch

12:30 PM – 1:40 PM (EDT) Bay Pines Pavilion
2:00 PM – 2:30 PM
Session 11

Cure HHT Updates: CHORUS and Research Roadmap Update

2:00 PM – 2:30 PM (EDT) Mansion Ballroom
Cassi Friday
Cassi Friday, PhD
Director, Research Programs and Grants
Cure HHT
2:30 PM – 4:00 PM
Session 12

HHT Research Roadmap: Small Working Groups

2:30 PM – 4:00 PM (EDT) Mansion Ballroom
6:00 PM – 11:30 PM
Gala

Awards Gala / Conference Dinner

6:00 PM – 11:30 PM (EDT) Carriage House
7:00 AM – 8:45 AM
Breakfast

General Breakfast

7:00 AM – 8:45 AM (EDT) Bay Pines Pavilion
9:00 AM – 9:15 AM
Opening

Welcome and Patient Story

9:00 AM – 9:15 AM (EDT)
9:15 AM – 11:20 AM
Session 13

Integrated Care, Imaging and Clinical Practice in HHT

9:15 AM – 11:20 AM (EDT) Mansion Ballroom
9:15 AM – 9:45 AM
Invited

AVIATOR

9:15 AM – 9:45 AM (EDT) Mansion Ballroom
Steve Hetts
Steve Hetts, MD
Chief of Neuroendovascular Surgery
University of California, San Francisco
11:20 AM – 11:35 AM
Session 14

Building an International HHT Center in Singapore

11:20 AM – 11:35 AM (EDT) Mansion Ballroom
Kristen Lee, MD
Department of Vascular and Interventional Radiology Singapore General Hospital
11:35 AM – 12:20 PM
Session 15

Sclerotherapy Demonstration

11:35 AM – 12:20 PM (EDT)
Dr. Piccirillo, MD
Professor and Vice-Chair Research
Department of Otolaryngology-Head and Neck Surgery, Washington University in St. Louis School of Medicine
12:20 PM – 1:00 PM
Lunch

Lunch

12:20 PM – 1:00 PM (EDT) Bay Pines Pavilion
1:00 PM – 2:00 PM
Session 16

The Future of Investigator-Initiated Research: AI, Knowledge, and the Next Generation of Scientific Discovery

1:00 PM – 2:00 PM (EDT) Mansion Ballroom
1:00 PM – 1:20 PM
Invited

Studytrax

1:00 PM – 1:20 PM (EDT) Mansion Ballroom
John Putzke, PhD
President
ScienceTRAX
2:00 PM – 3:00 PM
Closing

Closing & Awards

2:00 PM – 3:00 PM (EDT) Mansion Ballroom

Agenda current as of August 12, 2026.

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Conference Leadership

The 2026 HHT International Scientific Conference is guided by a leadership committee of respected experts who bring deep scientific, clinical, and strategic insight to every stage of planning. Their thoughtful direction helps ensure the program reflects the most pressing questions in HHT research and care, creates space for meaningful collaboration, and supports a program designed to move the field forward with purpose.

Steven W. Hetts,
MD, FACR
Co-Chair
Professor of Radiology, Biomedical Imaging, and Neurological Surgery University of California, San Francisco
Adrienne M. Hammill,
MD, PhD
Co-Chair
Professor of Clinical Pediatrics, University of Cincinnati College of Medicine Director, Cincinnati HHT Center of Excellence
Philippe Marambaud,
PhD
Co-Chair
Professor & Associate Director, Institute of Molecular Medicine The Feinstein Institutes, Northwell Health
S. Paul Oh,
PhD
Co-Chair
Professor and Co-Director, Barrow Aneurysm & AVM Research Center Barrow Neurological Institute
Cassi Friday,
PhD
 
Director, Research Programs and Grants Cure HHT
Marianne S. Clancy,
MPA
 
Chief Executive Officer & Senior Director, Strategic Partnerships Cure HHT

Thank You To Our 2026 Sponsors

Presenting

DiagonalLogo_DarkColor

Platinum

atavistik-bio-logo
Pharmacosmos-logo

Gold

alnylam-logo
Tectonic-Logo-full-color-300dpi
Terremoto_logo

Silver

Vaderis Therapeutics Logo

Bronze

Medtronic-logo