Philippe Marambaud, PhD 

Dr. Marambaud is Professor and Head of the Laboratory of Memory Disorders & Vascular Biology at the Feinstein Institutes, Northwell Health, in New York. He received his PhD in Biology from the University of Nice/Sophia-Antipolis, France, in 1998, followed by a postdoctoral fellowship at the Icahn School of Medicine at Mount Sinai in New York in 2000. He launched his faculty career at the Albert Einstein College of Medicine, Bronx, NY, in 2004, subsequently moving to the Feinstein Institutes, Manhasset, NY, as Laboratory Director in 2005. 

For over two decades, Dr. Marambaud has dedicated his research to unraveling the molecular basis of neuronal degeneration in Alzheimer’s disease and other dementias. In 2015, his laboratory significantly diversified its focus to encompass Hereditary Hemorrhagic Telangiectasia (HHT). Within this area, his lab is actively engaged in developing innovative human cell and mouse models of HHT with the goal of identifying effective drug repurposing strategies and novel disease-modifying interventions. This includes the creation of a novel HHT mouse model using blocking antibodies to mediate BMP9 and BMP10 loss-of-function. A testament to his team’s translational impact, they were instrumental in pinpointing tacrolimus, sirolimus, and nintedanib as promising drug candidates for HHT, all of which are now progressing through clinical trials to assess their efficacy in patients. 

Philippe Marambaud, PhD
Professor & Associate Director, Institute of Molecular Medicine
Co-Director, Litwin-Zucker Alzheimer’s Research Center
Head, Laboratory of Neuroscience and Vascular Biology
Leonard Litwin and Donald Zucker Endowed Professor of Geriatric Psychiatry
Professor of Molecular Medicine, Zucker School of Medicine at Hofstra/Northwell
The Feinstein Institutes for Medical Research at Northwell Health